From Framework to Field: Turning CIS Controls into Action with Sepio’s Asset DNA
From Framework to Field: Turning CIS Controls into Action with Sepio’s Asset DNA
From Policy to Proof
Every cybersecurity leader knows the CIS Critical Security Controls (CIS Controls). They’re one of the most widely adopted frameworks for improving cyber hygiene and reducing risk. But while most organisations document compliance, very few can prove it.
The reason? Their visibility stops at the software layer.
True implementation requires a complete view of hardware assets — the physical devices that support every system, connection, and user. That’s where Sepio’s Asset DNA technology, delivered in partnership with Zerium, transforms the CIS Controls from a checklist into a living, measurable defence framework.
CIS Controls: A Quick Refresher
The CIS Controls are a set of safeguards and best practices developed by the Center for Internet Security. They guide organisations toward prioritised, actionable improvements that reduce the most common cyber threats.
The first five — often called the Foundational Controls — are especially critical:
Inventory and Control of Enterprise Assets
Inventory and Control of Software Assets
Data Protection
Secure Configuration of Enterprise Assets and Software
Account Management
Every one of these controls assumes one fundamental capability: you can see and verify your assets. Without that visibility, compliance becomes theoretical — and risk management becomes reactive.
The Problem: CIS Controls Assume Hardware Visibility
Most compliance programmes rely on software-based discovery tools that track managed endpoints and applications. These tools work well for known assets but leave a vast blind spot at the hardware layer.
This leads to several hidden risks:
Unmanaged or rogue devices that connect undetected.
Spoofed peripherals that impersonate trusted hardware.
Shadow IT and IoT assets operating outside policy.
Supply-chain implants introduced during procurement.
Each of these breaks compliance with Control 1 (Inventory and Control of Enterprise Assets) — often without triggering an alert. To move from policy to proof, you need hardware DNA-level visibility — the ability to verify every physical device, not just the ones that report themselves.
Sepio’s Asset DNA: The Missing Piece in CIS Implementation
Sepio’s Asset Risk Management (ARM) platform introduces visibility where other tools stop.
Its patented Hardware DNA technology analyses the electrical and physical characteristics of every connected device, creating an immutable fingerprint that can’t be spoofed or cloned.
This unique approach provides:
Agentless discovery – No need to install software or disrupt operations.
Passive monitoring – Continuous hardware visibility across all environments.
Real-time risk scoring – Instantly identifies rogue or unauthorised assets.
Policy enforcement – Automatically blocks or isolates devices that don’t meet trust standards.
By integrating this visibility into your CIS Controls implementation, you replace assumptions with evidence — and documentation with data.
How Sepio + Zerium Operationalise the First Five CIS Controls
Below is a practical breakdown of how Zerium and Sepio help organisations implement the first five CIS Controls in the field.
Control 1: Inventory and Control of Enterprise Assets
Challenge: You can’t manage what you can’t see — especially unmanaged or rogue hardware.
Solution: Sepio discovers every connected device, using Hardware DNA to verify authenticity. Zerium aligns this visibility with your CIS asset management policies, ensuring your inventory is both accurate and auditable.
Control 2: Inventory and Control of Software Assets
Challenge: Rogue or unapproved hardware can run unverified software that escapes detection.
Solution: By identifying the hardware first, Sepio ensures that only authorised devices — and therefore authorised software — can operate in your environment.
Control 3: Data Protection
Challenge: Unverified hardware introduces data leakage risks and regulatory exposure.
Solution: Sepio blocks or isolates unauthorised devices, ensuring that only trusted hardware can access sensitive data or processing environments, aligning with GDPR and CIS requirements.
Control 4: Secure Configuration of Enterprise Assets and Software
Challenge: Devices configured outside of approved standards often enter networks undetected.
Solution: Zerium helps align hardware configuration baselines with CIS standards, while Sepio continuously validates that each device matches its approved fingerprint.
Control 5: Account Management
Challenge: Hardware-level impersonation undermines identity-based security models.
Solution: Hardware DNA provides a physical verification layer for devices associated with user accounts, preventing unauthorised access through spoofed endpoints.
Turning Compliance into Continuous Assurance
Implementing CIS Controls shouldn’t be a one-time project. With Sepio ARM, organisations achieve continuous compliance — hardware visibility that never stops monitoring.
Here’s how Zerium enables this in practice:
Integrate Sepio’s live asset data with your SIEM or compliance dashboards.
Automate alerts and policy enforcement for rogue hardware events.
Generate auditable reports that prove CIS Control alignment in real time.
Receive expert guidance from Zerium’s cybersecurity consultants on adapting your control environment as frameworks evolve.
This approach moves your organisation beyond compliance — toward operational assurance that scales with your infrastructure.
The Business Case for Hardware-Level CIS Compliance
Moving from paper compliance to hardware-level enforcement offers tangible business value:
Reduced risk: Rogue or unmanaged devices are identified before they cause harm.
Audit readiness: Real-time, verifiable asset data accelerates compliance reviews.
Operational efficiency: Fewer false positives and reduced manual asset tracking.
Regulatory alignment: Meets the asset visibility requirements of NIST, CISA BOD 23-01, and GDPR.
In short, CIS Controls become more than policy — they become provable.
Zerium: Turning Frameworks into Action
As a UK-based cybersecurity consultancy and authorised Sepio partner, Zerium helps organisations translate cybersecurity frameworks into operational controls. Their CIS implementation methodology includes:
Framework gap analysis and control mapping.
Sepio ARM deployment and configuration.
Customised policy alignment with CIS Controls 1–5.
Continuous monitoring, reporting, and enablement.
The result? Full lifecycle compliance — from framework interpretation to field execution.
Conclusion: Frameworks Are the Map — Visibility Is the Compass
The CIS Controls provide the roadmap for a secure enterprise. But without hardware-layer visibility, you’re navigating blind. By pairing Sepio’s Asset DNA technology with Zerium’s implementation expertise, organisations gain the power to:
See every device.
Verify every connection.
Enforce every control.
That’s how frameworks move from policy to proof — and from the boardroom to the battlefield of real-world cybersecurity.













